I thank the 14 Senators who contributed on the Order of Business. I completely agree with Senator Mark Daly on the need to transform the organ donation infrastructure. The committee I chaired in the last Oireachtas completed a comprehensive report on organ donation and, in particular, the need to change the model to a soft opt-out system. The Senator is right that that is part of the difficulty. Advertising or awareness raising will not meet the need for people to make organ donations. There is a need to change the infrastructure in dealing with the issue of dialysis in hospitals. The retirement of Dr. David Hickey has highlighted the vacuum. There is a need for consensus and a buy-in on all sides on organ donation. As somebody who, when in college, worked in a dialysis unit in Cork University Hospital, I am aware of the importance of the issue. I saw the range of emotions and trauma associated with dialysis and organ donation. The Senator is right that we need a change of approach to have a completely different system. I hope we can work to that end.

Senator Mark Daly also referred to Orkambi. He knows quite well that the National Centre for Pharmacoeconomics and the HSE make the decision. I am told that the HSE is involved in negotiations with the manufacturer of the drug to reduce the cost, particularly for cystic fibrosis patients. I agree with the Senator completely that we must look at ways by which we can make medications and life-changing or life-altering drugs available. Whether they are high-tech or high-cost is immaterial. It is about the preservation of life and the quality of life we can give, including to the people to whom the Senator referred. We have already done so with some of the cystic fibrosis drugs and other drugs used to treat multiple sclerosis. I do not see any reason we cannot see that change. It is important, therefore, that we keep the pressure on the Department and the HSE in the case of the drug to which the Senator referred.

Senator Victor Boyhan also raised the issue of organ donation.

With regard to Senator Mark Daly's Private Members' Bill which is to be taken this afternoon, I am not aware if the Minister will be in the House because he was away yesterday. I cannot give the Senator a definitive answer, but I am sure one of the Ministers of State will be present. I do not have an answer for the Senator on the issue of the payment made to the 4,000 people who are working overnight, but I will raise it with the Department.

Senator Rose Conway-Walsh raised the issue of social protection and said there was a need for the Minister for Social Protection to come to the House again to discuss it. To be honest, it might be appropriate to raise it in the debate on the Social Welfare Bill, but if I can arrange a stand-alone discussion, I will certainly try to do so.